Modeling the Heart and the Circulatory System
The book comprises contributions by some of the most respected scientists in the field of mathematical modeling and numerical simulation of the human cardiocirculatory system. The contributions cover a wide range of topics, from the preprocessing of clinical data to the development of mathematical equations, their numerical solution, and both in-vivo and in-vitro validation. They discuss the flow in the systemic arterial tree and the complex electro-fluid-mechanical coupling in the human heart. Many examples of patient-specific simulations are presented. This book is addressed to all scientists interested in the mathematical modeling and numerical simulation of the human cardiocirculatory system.
Ioannis V. Yannas
Tissue and Organ Regeneration in Adults: Extension of the Paradigm to Several Organs (2nd edition)
This textbook describes the basic principles of induced organ regeneration in skin and peripheral nerves and extends the original successful paradigm to other organs. A set of trans-organ rules is established and its use in regeneration of several organs is illustrated from the works of several independent investigators who worked with a variety of organs, such as the lung, the bladder, and the Achilles tendon, using collagen-based scaffolds somewhat similar to the original one. These critical medical treatments fill the clinical need that is not met by organ transplantation.
New to this second edition:
New information extending the paradigm of tissue regeneration from organ regeneration in skin and peripheral nerves to other organs
Guidelines, known as trans-organ rules, are described for the first time for extending this unique medical treatment to organs of several medical specialties
The work serves as a comprehensive text and reference for students and practitioners of tissue engineering
Robert B. Heimann, Hans D. Lehmann
Bioceramic Coatings for Medical Implants: Trends and Techniques
Reflecting the progress in recent years, this book provides in–depth information on the preparation, chemistry, and engineering of bioceramic coatings for medical implants. It is authored by two renowned experts with over 30 years of experience in industry and academia, who know the potentials and pitfalls of the techniques concerned.
Following an introduction to the principles of biocompatibility, they present the structures and properties of various bioceramics from alumina to zirconia. The main part of the work focuses on coating technologies, such as chemical vapor deposition, sol–gel deposition and thermal spraying. There then follows a discussion of the major interactions of bioceramics with bone or tissue cells, complemented by an overview of the in–vitro testing methods of the biomineralization properties of bioceramics. The text is rounded off by chapters on the functionalization of bioceramic coatings and a look at future trends.
As a result, the authors bring together all aspects of the latest techniques for designing, depositing, testing, and implementing improved and novel bioceramic coating compositions, providing a full yet concise overview for beginners and professionals.
Demons: Our changing attitudes to alcohol, tobacco, and drugs
Tabloid headlines attack the binge drinking of young women. Debates about the classification of cannabis continue, while major public health campaigns seek to reduce and ultimately eliminate smoking through health warnings and legislation. But the history of public health is not a simple one of changing attitudes resulting from increased medical knowledge, though that has played a key role, for instance since the identification of the link between smoking and lung cancer. As Virginia Berridge shows in this fascinating exploration, attitudes to public health, and efforts to change it, have historically been driven by social, cultural, political, and economic and industrial factors, as well as advances in science. They have resulted in different responses to drugs, alcohol, and tobacco at different times, in different parts of the world.
Opium dens in London, temperance and prohibition movements, the appearance of new recreational drugs in the 20th century, the changing attitudes to smoking: by taking us through such examples, moulded by socio-economic and political forces, including the growing power of pharmaceutical companies, Berridge illuminates current debates. While our medical knowledge has advanced, other factors help shape our responses, as they have done in the past.
Jan de Boer, Clemens A. van Blitterswijk
Materiomics: High-Throughput Screening of Biomaterial Properties
This complete, yet concise, guide introduces you to the rapidly developing field of high throughput screening of biomaterials: materiomics. Bringing together the key concepts and methodologies used to determine biomaterial properties, you will understand the adaptation and application of materomics in areas such as rapid prototyping, lithography and combinatorial chemistry. Each chapter is written by internationally renowned experts, and includes tutorial paragraphs on topics such as biomaterial-banking, imaging, assay development, translational aspects, and informatics. Case studies of state-of-the-art experiments provide illustrative examples, whilst lists of key publications allow you to easily read up on the most relevant background material. Whether you are a professional scientist in industry, a student or a researcher, this book is not to be missed if you are interested in the latest developments in biomaterials research.