Hildebert Wagner, Rudolf Bauer, Dieter Melchart, Pei-Gen Xiao, Anton Staudinger
Chromatographic Fingerprint Analysis of Herbal Medicines: Thin-layer and High Performance Liquid Chromatography of Chinese Drugs (2nd edition)
This manual, to be published in two volumes, provides a condensed overview of the analytical investigation of 80 Chinese Herbal Drugs which are most frequently in use. Thin layer chromatographic-, high pressure liquid chromatographic- and gas chromatographic-fingerprint analytical techniques allow the detection of all main low-molecular constituents of a plant drug and even single constituents can be visualized. Analytical results thereof are shown in numerous color figures. The quality proof of the investigation meets the standard of the European Drug Regulatory Authority.Furthermore, this volume gives a detailed description of the analytical methods used for several drugs. Bioactive constituents, pharmacological and biological activities of several single herbal drugs as well as their therapeutic applications are discussed.
Lara V. Marks
The Lock and Key of Medicine: Monoclonal Antibodies and the Transformation of Healthcare
This book is the first to tell the extraordinary yet unheralded history of monoclonal antibodies. Often referred to as Mabs, they are unfamiliar to most nonscientists, yet these microscopic protein molecules are everywhere, quietly shaping our lives and healthcare. Discovered in the mid-1970s in the laboratory where Watson and Crick had earlier unveiled the structure of DNA, Mabs have radically changed understandings of the pathways of disease. They have enabled faster, cheaper, and more accurate clinical diagnostic testing on a vast scale. And they have played a fundamental role in pharmaceutical innovation, leading to such developments as recombinant interferon and insulin, and personalized drug therapies such as Herceptin. Today Mabs constitute six of the world’s top ten blockbuster drugs and make up a third of new introduced treatments. Lara V. Marks recounts the risks and opposition that a daring handful of individuals faced while discovering and developing Mabs, and she addresses the related scientific, medical, technological, business, and social challenges that arose. She offers a saga of entrepreneurs whose persistence and creativity ultimately changed the healthcare landscape and brought untold relief to millions of patients. Even so, as Marks shows, controversies over Mabs remain, and she examines current debates over the costs and effectiveness of these innovative drugs.
Atherosclerosis and Heart Disease
Exploring the entire range of recent advances, Atherosclerosis and Heart Disease covers all aspects of atherosclerotic disease, including chronic manifestations, bypass surgery, stroke prevention and methods to lower blood pressure. Prof. Tonkin brings together a team of internationally-recognized experts to discuss sound clinical practices, based on scientific research and publications. They examine conventional and novel risk factors, acute coronary syndromes, and chronic manifestations of disease. The book provides a broad perspective on the disease process as it affects the patients doctors see every day and outlines current therapeutic strategies. It includes coverage of topics such as blood pressure and blood pressure-lowering therapy, lipid-modifying therapy, risk management strategies, and medical management of angina pectoris.
Anthony A. Nash
Mims’ Pathogenesis of Infectious Disease, Fifth Edition
Mims’ Pathogenesis of Infectious Disease is the landmark book in the field of infectious disease. The new, revised edition of this work provides a comprehensive, up-to-date description of the mechanisms of microbial infection and the pathogenesis of infectious disease. Presented in a clear, accessible style, it deals in an integrated manner with the spectrum of microorganisms, describing the factors common to all infectious diseases. Molecular biology, pathology, and immunology are brought together to explain the mechanisms for spread, immune response, and recovery.
Key features and of the 5th edition include:
* Microbial gene sequencing
* Up-to-date picture of the global burden of infectious diseases
* Role of bacterial virulence factors in vivo, as contrasted with possibilities based on in vitro evidence
* Latest data on combination vaccines, the promise of edible vaccines
* The spread of antibiotic resistance genes among bacteria
* HIV1 and HIV2 molecular biology, pathogenesis and origin
Novak and Berek’s Gynecology 14e (Hb)
The gold standard text in gynecology is in its Fourteenth Edition, thoroughly revised and updated and now in full color throughout. Organized into eight sections, this comprehensive and general gynecological textbook provides guidance for the management of specific gynecological conditions.