Salmonella Enterica


Salmonella Enterica: Molecular Characterization, Role in Infectious Diseases and Emerging Research
Viruses : Agents of Evolutionary Invention
World Health Organization, “Handbook IMCI Integrated Management of Childhood Illness”
Elka Touitou, Brian W. Barry, “Enhancement in Drug Delivery”
Hans G. Beger and Andrew L. Warshaw, “The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery”

Salmonella Enterica: Molecular Characterization, Role in Infectious Diseases and Emerging Research

Nova | English | 2018 | ISBN-10: 1536130842 | 144 pages | PDF | 2.93 mb

by Faruk Van Doleweerd (Editor)
The bacterium Salmonella enterica is a serious bacterial pathogen and causative agent of salmonellosis infections on a worldwide scale. Many clinical isolates of S. entericaS. enterica. Following this, the strengths and limitations of the available molecular tools for effective epidemiological assessment of foodborne salmonellae are collected and critically discussed. Such integration would allow accurate identification of both infection source and transmission route that would lead to implementation of effective control measures. Additionally, the role of Salmonella enterica as a possible therapeutic alternative in the fight against cancer. Although Salmonella enterica tumor selectivity remains unclear, pre-clinical and clinical trials have shown its localization in solid, semi-solid and metastatic tumors. The final chapter reviews some mechanisms and recent trends in the spread of multidrug resistant Salmonella enterica. serovar in Nigeria. Antibiotic use both in animal and human medicine and environmental factors, all have a role in the emergence, persistence and spread of resistance.
Series: Bacteriology Research Developments

Viruses : Agents of Evolutionary Invention

English | 2017 | ISBN: 0674972082 | 385 Pages | PDF | 21 MB

Viruses are the most abundant biological entities on Earth, and arguably the most successful. They are not technically alive, but – as infectious vehicles of genetic information – they have a remarkable capacity to invade, replicate, and evolve within living cells. Synthesizing a large body of recent research, Michael Cordingley goes beyond our familiarity with viral infections to show how viruses spur evolutionary change in their hosts, shape global ecosystems, and influence every domain of life.
In the last few decades, research has revealed that viruses are fundamental to the photosynthetic capacity of the world’s oceans and the composition of the human microbiome. Perhaps most fascinating, viruses are now recognized as remarkable engines of the genetic innovation that fuels natural selection and catalyzes evolution in all domains of life. Viruses have coevolved with their hosts since the beginning of life on our planet and are part of the evolutionary legacy of every species that has ever lived.
Cordingley explains how viruses are responsible for the creation of many feared bacterial diseases and the emergence of newly pathogenic and drug-resistant strains. And as more and more viruses jump to humans from other animals, new epidemics of viral disease will threaten global society. But Cordingley shows that we can adapt, relying on our evolved cognitive and cultural capacities to limit the consequences of viral infections. Piecing together the story of viruses’ major role within and beyond human disease, Viruses creates a valuable roadmap through the rapidly expanding terrain of virology.

World Health Organization, “Handbook IMCI Integrated Management of Childhood Illness”

English | 2006 | ISBN: 9241546441 | PDF | pages: 173 | 1.2 mb

The WHO/UNICEF guidelines for Integrated Management of Childhood Illness offer simple and effective methods to prevent and manage the leading causes of serious illness and mortality in young children. The clinical guidelines promote evidence-based assessment and treatment using a syndromic approach that supports the rational, effective, and affordable use of drugs. The IMCI model handbook provides a detailed explanation of the IMCI case management guidelines. It is organized into seven main parts: overview of the IMCI process; assess and classify the sick child age 2 months up to 5 years; assess and classify the sick young infant age 1 week up to 2 months; identify treatment; treat the sick child or the sick young infant; communicate and counsel; and give follow-up care.
The IMCI charts and related in-service training materials provided in this handbook are considered to be a generic version. The WHO Department of Child and Adolescent Health and Development created this handbook to help teaching institutions incorporate IMCI into academic programs for doctors, nurses and other health professionals. Teaching institutions are advised to adapt the handbook in two ways: (1) to ensure that all text charts and illustrations are consistent with nationally-adapted IMCI clinical guidelines, and (2) to ensure that its content and format corresponds to the teaching approach used by the institution.

Elka Touitou, Brian W. Barry, “Enhancement in Drug Delivery”

English | 2006 | ISBN: 0849332036 | PDF | pages: 652 | 10.3 mb

Providing a significant cross-fertilization of ideas across several disciplines, Enhancement in Drug Delivery offers a unique comprehensive review of both theoretical and practical aspects of enhancement agents and techniques used for problematic administration routes. It presents an integrated evaluation of absorption enhancers and modes for promoting absorption that is especially valuable to those involved with the development of pharmaceutical, cosmetic, bioengineered, and medical products, as well as graduate students looking to study this intriguing field and those professionals involved with patents and regulatory issues.
Organized by routes of administration, the book is divided into eight major sections: oral, rectal, buccal/sublingual, dermal/transdermal, nasal, vaginal/uterine, ocular, and brain. It offers fundamental as well specialized information including current findings on―
· Surfactant use to accelerate macromolecule input
· Targeted gastrointestinal delivery and enhanced absorption of lipophilic drugs
· Permeation issues in rectal absorption
· Chemical means of enhancement
· Carriers for enhanced delivery to and across the skin
· Methods associated with breaching the skin
· Promoted buccal and sublingual absorption
· Emerging ocular, nasal, vaginal, and uterine delivery systems
· Carriers for overcoming the blood brain barrier
Those investigators primarily involved with one specific route of delivery will be able to learn of helpful concepts and find additional stimulation from reading the approaches others have used within and outside their own spheres of activity. Readers are likely to find the same enhancer tested for various administration routes and in diverse experimental models. By understanding the properties and behavior of the enhancers operating within such systems, they may well find the inspiration needed to develop appropriate enhancing delivery methods for new applications.

Hans G. Beger and Andrew L. Warshaw, “The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery”

English | ISBN: 1119188393 | 2018 | 1216 pages | PDF | 42 MB

This brand new updated edition of the most comprehensive reference book on pancreatic disease details the very latest knowledge on genetics and molecular biological background in terms of anatomy, physiology, pathology, and pathophysiology for all known disorders. Included for the first time, are two brand new sections on the key areas of Autoimmune Pancreatitis and Benign Cystic Neoplasms. In addition, this edition is filled with over 500 high–quality illustrations, line drawings, and radiographs that provide a step–by–step approach to all endoscopic techniques and surgical procedures. Each of these images can be downloaded via an online image bank for use in scientific presentations.
Every existing chapter in The Pancreas: An Integrated Textbook of Basic Science, Medicine and Surgery, 3rd Edition has been thoroughly revised and updated to include the many changes in clinical practice since publication of the current edition. The book includes new guidelines for non–surgical and surgical treatment; new molecular biologic pathways to support clinical decision making in targeted treatment of pancreatic cancer; new minimally invasive surgical approaches for pancreatic diseases; and the latest knowledge of neuroendocrine tumors and periampullary tumors.
The most encyclopedic book on the pancreas providing outstanding and clear guidance for the practicing clinician
Covers every known pancreatic disorder in detail including its anatomy, physiology, pathology, pathophysiology, diagnosis, and management
Completely updated with brand new chapters
Over 500 downloadable illustrations
An editor and author team of high international repute who present global best–practice
The Pancreas: An Integrated Textbook of Basic Science, Medicine and Surgery, 3rd Edition is an important book for gastroenterologists and gastrointestinal surgeons worldwide.

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